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C7821 Sigma

Curdlan from Alcaligenes faecalis

Synonym: β-1,3-Glucan hydrate

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Description

Biochem/physiol Actions

Curdlan is a (1,3)-β-glucan. It is a pathogen-associated molecular-pattern (PAMP) recognized by the receptor dectin-1. Activation of dectin-1, together with TLR2/TLR6, promotes signaling resulting in the production of pro-inflammatory cytokines, thus inducing inflammation.

Packaging

5 g in glass bottle

Preparation Note

For gelation at 70 °C, the concentration of the sodium hydroxide should be 0.01 M.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Do you test to confirm that product C7821, Curdlan,has(1,3)-β-glucan linkages?
We do not test to confirm that C7821, Curdlan, has (1,3)-β-glucan linkages on a lot to lot basis. However, we have verified product authenticity in the past. Our manufacturing procedure is reported in literature as yielding Curdlan. In addition, C13-NMR, chromatography, and IR analyses results compared to literature and commercial control product proved that product is a (1,3)-β glucan polymer.
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Protocols & Articles

Articles

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Peer-Reviewed Papers
15

References

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