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C8261 Sigma

Sodium chenodeoxycholate


Synonym: 3α,7α-Dihydroxy-5β-cholanic acid, 5β-Cholanic acid-3α,7α-diol, Chenodeoxycholic acid sodium salt, Chenodesoxycholic acid, Chenodiol



Related Categories Anionic Detergents, Bile Salts, Biochemicals and Reagents, Cell Culture, Detergents,
description   anionic
assay   ≥97%


Biochem/physiol Actions

Bile Salt

General description

Sodium chenodeoxycholate is a bile salt, which has been shown to accelerate colonic transit and improve bowel function.


1 g in glass bottle

500 mg in glass bottle


Sodium chenodeoxycholate has been used in a study to assess DNA repair response in the bacterium Escherichia coli. It has also been used in a study to investigate the physical and chemical factors influencing germination of Clostridium difficile spores.

Price and Availability

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Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles


Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

Bile Salts and Bile Salt Hydrolase

Several Lactobacillus and Bifidobacterium probiotic strains exhibit bile salt hydrolase (BSH) activity and are suspected to play a role in combating the negative effects of bile via detoxification of...
Chloe McClanahan
Biofiles Edition 6.2
Keywords: Detoxification, Probiotics, Thin layer chromatography, Titrations

Detergent Properties and Applications

The key to detergent function is an amphipathic structure. All detergents are characterized as containing a hydrophilic “head” region and a hydrophobic “tail” region (see Figure 1).
Vicki Caligur
BioFiles 2008, 3.3, 14.
Keywords: Adsorption, Biochemistry, Cell disruption, Chromatography, Crystallization, Detergents, Diagnostic, Dialysis, Electrophoresis, Enzymology, Filtration, Mass spectrometry, Normal-phase chromatography, Nucleic acid denaturation, Precipitation, Purification, Separation, Size-exclusion chromatography

Probiotics and Human Health

At the beginning of the 20th century, probiotics were thought to have a beneficial effect to the host by improving the intestinal microbial balance. Through his studies and observations, the Russian ...
Chloe McClanahan
BioFiles Edition 6.2
Keywords: AGE, Absorption, Adhesion, Amplification, Anaerobic, Antimicrobials, Apoptosis, Cancer, Capillary electrophoresis, Carcinogens, Cell culture, Cell proliferation, Chromatography, Coagulation, Detoxification, Diagnostic, Diseases, Enzyme activity, Fermentation, Gas chromatography, Gastrointestinal, Genomics, High performance liquid chromatography, Immunology, Inflammation, Magnetic resonance spectroscopy, Metabolism, Metabolites, Microbiology, Molecular biology, Nucleic acid hybridization, Pharmaceutical, Phosphorylations, Polymerase chain reaction, Polymerase chain reaction - quantitative, Prebiotics, Probiotics, Reductions, Respiratory, Sequencing, Thin layer chromatography, Titrations

Peer-Reviewed Papers


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