EMAIL THIS PAGE TO A FRIEND
C8667 Sigma-Aldrich

Cholesterol

Sigma Grade, ≥99%

Synonym: 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol

  • CAS Number 57-88-5

  • Empirical Formula (Hill Notation) C27H46O

  • Molecular Weight 386.65

  •  Beilstein Registry Number 1915888

  •  EC Number 200-353-2

  •  MDL number MFCD00003646

  •  eCl@ss 39023139

  •  PubChem Substance ID 24893094

Purchase

Description

Biochem/physiol Actions

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Cholesterol is a lipid that makes up about 20-25% of the structural components of the cell membranes. It determines the fluidity and permeability of the membrane, making it permeable to water but not to ions and protons. Cholesterol also regulates the functions of the transporters and signaling proteins present on the plasma membrane. The major sites of cholesterol synthesis are small intestine and liver.

Packaging

1, 5, 25, 100 g in poly bottle

500 mg in poly bottle

Preparation Note

Cholesterol monohydrate yields a clear, colorless to faint yellow solution in hot alcohol. It is also soluble in acetone, dioxane, ethyl acetate, benzene, petroleum ether, oils, fats, and in aqueous solutions of bile salts. Solutions should be protected from light.

Application

Cholesterol was used to prepare immune-stimulating complexes to enhance cellular and humoral responses. It was incorporated in animal feed to study the effect of cholesterol-rich diet.

Other Notes

Add your comments, questions, and reviews about this product.

See what your peers are saying about this product.

Safety & Documentation

Same Products - New Packaging
Protocols & Articles

Articles

Cholesterol Biosynthesis

Cholesterol levels in the body come from two sources, dietary intake and biosynthesis. The majority of cholesterol utilized by healthy adults is synthesized in the liver, which produces ~70% of the t...
BioFiles 2007, 2.7, 3.
Keywords: Catalysis, Decarboxylations, Metabolic Pathways, Oxidations, PAGE, Phosphorylations, Reductions

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

488577 Cholesterol-2,2,3,4,4,6-d6, 97 atom % D, 98% (CP)
749478 Cholesterol-2,3,4-13C3, 99 atom % 13C, 98% (CP)
06693 Timestrip Plus -20 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?