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C9282 Sigma-Aldrich

Sodium cholate hydrate

BioReagent, suitable for cell culture

Synonym: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid sodium salt, Cholalic acid sodium salt

  • CAS Number 206986-87-0

  • Empirical Formula (Hill Notation) C24H39NaO5 · xH2O

  • Molecular Weight 430.55 (anhydrous basis)

  •  Beilstein/REAXYS Number 3582354

  •  EC Number 206-643-5

  •  MDL number MFCD00150749

  •  PubChem Substance ID 24893147

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Properties

Related Categories Anionic Detergents, Antigen-Vaccine Preparation, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents,
description   anionic
InChI Key   MUVVIYFKOVLQHL-RCVKHMDESA-M
product line   BioReagent
assay   ≥99.0% (HPLC)
mol wt   micellar avg mol wt 900-1300
aggregation number   2-3
CMC   9-15 mM (20-25°C)
HLB   18
suitability   suitable for cell culture

Description

Application

Cholate is a bile acid produced in liver during cholesterol breakdown. Cholate downregulates cholesterol-7-α-hydroxylase (rate-limiting step in bile acid synthesis). Cholate, an anionic detergent, is used alone and in combination with urea to extract and reconstitute membrane proteins and protein complexes.

Non-denaturing detergent used for extraction of membrane proteins.

Packaging

25, 100 g in poly bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles
Peer-Reviewed Papers
15

References

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U0631 Urea, BioXtra, pH 7.5-9.5 (20 °C, 5 M in H2O)

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