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C9301 Sigma-Aldrich

Collagen from chicken sternal cartilage

Type II (Miller), powder, BioReagent, suitable for cell culture



Related Categories Adhesion, Attachment, and Matrix Factors for Stem Cell Expansion, Application Index, Attachment Factors, Attachments Factors, Biochemicals and Reagents,
Quality Level   300
biological source   chicken (Sternal cartilage)
sterility   non-sterile
type   Type II (Miller)
product line   BioReagent
assay   60-80% (biuret)
form   powder
packaging   glass bottle of 100 mg
  poly bottle of 25 mg
  glass bottle of 5 mg
application(s)   cell culture | mammalian: suitable
surface coverage   6‑10 μg/cm2
solubility   acetic acid: 0.5-2.0 mg/mL (Dissolve for several hours at 2-8 °C, occasionally swirling.)
shipped in   wet ice
storage temp.   2-8°C
Gene Information   chicken ... COL2A1(395069)


General description

Collagen is made of three polypeptide chains. Type 2 collagen is ubiquitously present in the hyaline cartilage. It is a homotrimer made of three α1 chains. Type 2 collagen is also predominant in nucleus pulposus of the vertebral disc and vitreous body of the eye. The proteoglycan obtained from the chicken sternal cartilage is similar to type nine collagen structure.

Collagen is classified into a number of structurally and genetically distinct types. We use the nomenclature proposed by Bornstein and Traub. Do not confuse Sigma type designations with recognized collagen classification types.


Collagen from chicken sternal cartilage has been used in enzyme–linked immunosorbent assay (ELISA) , chondrocyte-mediated tissue production in vitro, induction, treatment and assessment of collagenα induced arthritis (CIA) and cell proliferation assay.


100 mg in glass bottle

25 mg in poly bottle

5 mg in glass bottle

Other Notes

Major component of articular cartilage.

Preparation Note

Prepared by a modification of the method of Trentham, D.E., et al.

Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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