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  • C9687 - Monoclonal Anti-Cytokeratin, pan (Mixture) Prediluted antibody produced in mouse

C9687 Sigma-Aldrich

Monoclonal Anti-Cytokeratin, pan (Mixture) Prediluted antibody produced in mouse

clone C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, ascites fluid

Synonym: Monoclonal Anti-Cytokeratin, pan (mixture)



conjugate   unconjugated
clone   C-11+PCK-26+CY-90+KS-1A3+M20+A53-B/A2, monoclonal
biological source   mouse
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  immunohistochemistry (frozen sections): suitable
species reactivity   wide range
shipped in   dry ice
storage temp.   −20°C
antibody form   ascites fluid
isotype   IgG1/IgG2a
Quality Level   200
antibody product type   primary antibodies


General description

Cytokeratins are cytoplasmic structural proteins that are characteristic of epithelial and trichocytic cells. The group contains at least 29 different proteins.


This is a mixture of monoclonal anti-cytokeratin antibodies. It recognizes human cytokeratins 1,4,5,6,8,10,13,18, and 19. It is a broad spectrum reagent, which reacts specifically with a wide variety of normal, reactive, and neoplastic epithelial tissues. The antibody mixture reacts with simple, cornifying and non-cornifying squamous epithelia and pseudostratified epithelia. It does not react with non-epithelial normal human tissues. Increased staining intensity is seen following proteolytic treatment (protease unmasking).


mixture of several monoclonal cytokeratin clones.


Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunohistochemistry (1 paper)

Monoclonal Anti-Pan Cytokeratin (mixture) produced in mouse is suitable for immunohistochemistry (formalin-fixed, paraffin-embedded sections), immunoblotting and dot blotting. It is also useful for staining of cultured epithelial cell lines. Staining can be amplified by synergy between the various components and this enables identification of cells which would otherwise be stained only marginally. It aids in the discrimination of carcinomas and non-epithelial tumors like sarcomas, lymphomas, and neural tumors. It detects micrometastases in lymph nodes, bone marrow, and other tissues and may be used for determining the origin of poorly differentiated tumors. The mixture recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic, and neoplastic cells. It was used for immunostaining in a study to demonstrate differential expression and function of cadherin-6 during renal epithelium development. It was used for whole mount immunofluorescence to detect cytokeratin and for visualization of nephric duct derivatives in a study.

Physical form

Prediluted containing horse serum, phenol red, and 15 mM sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


This product is similar to C2562, but is offered prediluted and ready to use.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers


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