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C9755 Sigma-Aldrich

Cytidine 5′-diphosphate sodium salt hydrate

from yeast, ≥95%

Synonym: CDP sodium salt hydrate

  • Empirical Formula (Hill Notation) C9H15N3O11P2

  • Molecular Weight 403.18

  •  MDL number MFCD00069770

  •  PubChem Substance ID 24893191

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cofactors, Enzymes, Inhibitors, and Substrates, Metabolic Pathways,
Quality Level   200
biological source   yeast
assay   ≥95%
storage temp.   −20°C
SMILES string   [Na].NC1=NC(=O)N(C=C1)C2OC(COP(O)(=O)OP(O)(O)=O)C(O)C2O
InChI   1S/C9H15N3O11P2.Na.H/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(22-8)3-21-25(19,20)23-24(16,17)18;;/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H2,10,11,15)(H2,16,17,18);;
InChI key   MAGSIBHRUIBONY-UHFFFAOYSA-N

Description

General description

Cytidine 5′-diphosphate (CDP) is synthesized from cytidine monophosphate (CMP) or uridine monophosphate (UMP) by the transfer of phosphoryl group, catalyzed by the enzyme uridylate kinase (UMPK). CTP synthetase catalyzes the conversion of CTP to CDP intermediates like CDP-diacylglycerol, CDP-choline and CDP-ethanolamine for phospholipid biosynthesis.

Application

Cytidine 5′-diphosphate sodium salt hydrate has been used:
•  as a substrate in nucleoside diphosphatase (NDPase) enzyme histochemistry assay of gold fish eye sections
• in ribonucleotide reductase assay
• dCDP formation assay.

Packaging

25, 100 mg in poly bottle

Biochem/physiol Actions

Cytidine 5′-diphosphate (CDP) is used as a substrate of nucleoside diphosphatase kinase to produce CTP for supporting DNA and RNA biosynthesis and of ribonucleotide reductase to product dCMP.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

LC/MS Analysis of Nucleotides SeQuant ZIC-cHILIC – Effect of pH

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Nucleotides SeQuant ZIC-cHILIC – Effect of pH
Keywords: High performance liquid chromatography, Mass spectrometry

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC – Effect of Mobile Phase Buffer Concentration

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC – Effect of Mobile Phase Buffer Concentration
Keywords: High performance liquid chromatography, Mass spectrometry

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC
Keywords: Buffers, Building blocks, Chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Reversed-phase chromatography, Separation

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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