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Corning® Osteo Assay Surface Multiple Well Plate

size 96 well, flat bottom clear, pkg of (individually wrapped), pkg of (4/case), sterile, lid

Synonym: 96 well cell culture plates, cell culture plates, tissue culture plates

  •  NACRES NB.13



Related Categories 96 Well Plates, Corning, Corning 96-Well Assay Plates, Corning 96-Well Microplates, Corning 96-Well Multiwell Plates,
material   clear bottom
  flat bottom clear
sterility   sterile
feature   lid
  plate format: 96 well standard
mfr. no.   Corning, 3988
packaging   pkg of (4/case)
  pkg of (individually wrapped)
size   96 well
well volume   360 μL
well working volume   75-200 μL
wells   96 wells
color   clear
matrix active group   Osteo Assay surface surface treatment
surface area   0.32 cm2 (cell growth area)
suitability   suitable for (Osteoclast and Osteoblast differentiation and function studies)
binding type   (Osteo Assay Surface)


General description

•  Bone biomimetic synthetic surface
• Inorganic, non-biological
• Compatible with osteoblast and osteoclast differentiation and functional studies
• Co-culture of ostoeclast and osteoblast with other cell lines
• 96 well format uniformly coated
• Flat bottoms
• Recommended working volume 75 to 200 μL
• Nonreversible lids with condensation rings to reduce contamination
• Individual alphanumeric codes for well identification
• •ndividually wrapped
• Sterilized by gamma irradiation

Corning Osteo Assay Surface multiple well plates can be used to assess cell functional activity in response to drug treatment. Research related to basic osteoblast biology focuses on cell differentiation and function. Osteoblasts are of mesenchymal origin. Several growth factors have been implicated in osteoblast differentiation, including bone morphogenic proteins (BMPs) and Indian hedgehog. Additionally, several hormones are believed to play an important role in bone formation, including estradiol, parathyroid hormone and leptin. Osteoblast differentiation on the new Corning Osteo Assay Surface provides an in vivo-like surface for improved osteoblast growth and differentiation.

Understanding the biology of bone disease is of critical importance to the aging population. Due to the difficult nature of the assays involved in studying bone, scientists have long been limited with regard to the methods, available formats and throughput used in this area of research. Corning Life Sciences has developed a new platform to aid researchers with their bone studies that is consistent and repeatable. The Corning Osteo Assay Surface multiple well plates are coated with a proprietary synthetic inorganic bone mimetic, which allows the direct assessment of osteoclast and osteoblast activity in vitro. This surface permits easy and reliable quantification of results in a format that is amenable to drug screening, as well as basic research applications.

Osteo Surface

• Assess cell functionality in response to drug treatment
• in vivo-like surface for osteoblast growth and differentiation
• Synthetic inorganic bone mimetic surface
• Direct assessment of osteoclast and osteoblast activity in vitro
• Surface amenable to drug screening and other basic research applications

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Corning is a registered trademark of Corning, Inc.

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