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D0195 Sigma-Aldrich

Dimethylethylammoniumpropane sulfonate

≥97% (TLC)

Synonym: NDSB 195

  • CAS Number 160255-06-1

  • Empirical Formula (Hill Notation) C7H17NO3S

  • Molecular Weight 195.28

  •  NACRES NA.25

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Description

General description

Dimethylethylammoniumpropane sulfonate is a zwitterionic solubilizing agent with usefulness in protein crystallization.

Application

Dimethylethylammoniumpropane sulfonate has been used in a study to assess the functional properties of the separate subunits of the human DNA helicase II/Ku autoantigen. It has also been used in a study to investigate the swelling behaviors of copolymeric hydrogels in various saline solutions.

Non-detergent sulfobetaine is a compound used for non-denaturing protien purification. Increases the extraction yield of membrane, nuclear and cytoskeletal associated proteins. Zwitterionic over a wide pH range, easily removed by dialysis and no significant absorption in the near UV range. Specific applications include microsomal protein extraction, nuclear protein recovery, precipitation reduction in IEF, and membrane-bound protease purification.

Packaging

5 g in poly bottle

Other Notes

This product is non-micelle forming.

Safety & Documentation

Safety Information

RIDADR 
UN 3261 8 / PGIII
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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