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D033 Sigma-Aldrich

(+)-Butaclamol hydrochloride

  • CAS Number 55528-07-9

  • Empirical Formula (Hill Notation) C25H31NO · HCl

  • Molecular Weight 397.98

  •  MDL number MFCD00082307

  •  PubChem Substance ID 24278400

  •  NACRES NA.77

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Properties

Related Categories Antagonists - Dopaminergics, B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
Quality Level   100
optical activity   [α]27/D +222° in methanol(lit.)
color   white
solubility   DMSO: >10 mg/mL, clear
SMILES string   Cl[H].[H][C@@]12C[C@@](O)(CCN1C[C@@]3([H])c4ccccc4CCc5cccc2c35)C(C)(C)C
InChI   1S/C25H31NO.ClH/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25;/h4-10,21-22,27H,11-16H2,1-3H3;1H/t21-,22-,25-;/m0./s1
InChI key   QZRUMKUMFJJARD-AAJWHBHYSA-N
Gene Information   human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816)

Description

Application

(+)-Butaclamol hydrochloride has been used as a dopamine receptor blocker in:
• dissected brain sections
• striatum of Parkinson′s disease specimens
• human embryonic kidney cells (HEK293 cells)
• mice striatal tissue

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

(+)-Butaclamol is a dopamine receptor antagonist and is an active enantiomer.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
DE8039700
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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