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D0444 Sigma-Aldrich

DT-2 trifluoroacetate salt

≥95% (HPLC), film

  • Empirical Formula (Hill Notation) C122H223N53O23 · xC2HF3O2

  • Molecular Weight 2800.42 (free base basis)

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY,
Quality Level   200
assay   ≥95% (HPLC)
form   film
composition   Peptide content, ≥60%
color   colorless to white
solubility   H2O: 0.5 mg/mL, clear
shipped in   wet ice
storage temp.   −20°C

Description

Amino Acid Sequence

Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Leu-Arg-Lys-Lys-Lys-Lys-Lys-His-NH2

Packaging

250 μg in glass bottle

Biochem/physiol Actions

Cell permeable cGMP protein kinase (PKG) inhibitor

Features and Benefits

This compound is featured on the PKA & PKG page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

PKA & PKG

Cyclic AMP-dependent protein kinase (PKA or cAK) and cyclic GMP-dependent protein kinase (PKG or cGK) transfer the γ-phosphate of ATP to serine and threonine residues of many cellular proteins. PKAs ...
Keywords: Atomic absorption spectroscopy, Catalysis, Cell proliferation, Diabetes, Gene expression, Hormones, Ligands, Myristoylations, Neurotransmitters, Phosphorylations, Positron Emission Tomography

Peer-Reviewed Papers
15

References

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