• USA Home
  • D1285 - 2′,3′-Dideoxyadenosine

EMAIL THIS PAGE TO A FRIEND
D1285 Sigma-Aldrich

2′,3′-Dideoxyadenosine

≥97% (HPLC)

Synonym: ddA

  • CAS Number 4097-22-7

  • Empirical Formula (Hill Notation) C10H13N5O2

  • Molecular Weight 235.24

  •  Beilstein/REAXYS Number 619924

  •  EC Number 223-853-2

  •  MDL number MFCD00010534

  •  PubChem Substance ID 24893397

Purchase

Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
Quality Level   200
assay   ≥97% (HPLC)
form   powder
optical activity   [α]/D -28.0±1.0
mp   181-184 °C (lit.)
solubility   water: 100 mg/mL, clear, colorless
storage temp.   2-8°C
SMILES string   Nc1ncnc2n(cnc12)[C@H]3CC[C@@H](CO)O3
InChI   1S/C10H13N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h4-7,16H,1-3H2,(H2,11,12,13)/t6-,7+/m0/s1
InChI key   WVXRAFOPTSTNLL-NKWVEPMBSA-N
Gene Information   human ... DCK(1633)

Description

General description

2′,3′-Dideoxyadenosine is a nucleoside analog of deoxyadenosine. On deamination, it is converted to dideoxyinosine. It inhibits adenylyl cyclase and may play a key role in the inhibition of tumor progression. It is a potent inhibitor of reverse transcriptase enzyme of human immunodeficiency virus.

Application

2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation.

Packaging

5, 25 mg in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
AU7358900
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?