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D1285 Sigma-Aldrich

2′,3′-Dideoxyadenosine

≥97% (HPLC)

Synonym: ddA

  • CAS Number 4097-22-7

  • Empirical Formula (Hill Notation) C10H13N5O2

  • Molecular Weight 235.24

  •  Beilstein/REAXYS Number 619924

  •  EC Number 223-853-2

  •  MDL number MFCD00010534

  •  PubChem Substance ID 24893397

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Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
InChI Key   WVXRAFOPTSTNLL-NKWVEPMBSA-N
Quality Level   200
assay   ≥97% (HPLC)
mp   181-184 °C (lit.)
storage temp.   2-8°C
Gene Information   human ... DCK(1633)

Description

General description

2′,3′-Dideoxyadenosine is a nucleoside analog of deoxyadenosine. On deamination, it is converted to dideoxyinosine. It inhibits adenylyl cyclase and may play a key role in the inhibition of tumor progression. It is a potent inhibitor of reverse transcriptase enzyme of human immunodeficiency virus.

Application

2′,3′-Dideoxyadenosine (ddA), a specific adenylyl cyclase inhibitor, is useful in biological process and pathway studies involving adenylyl cyclase activity and cAMP pool modulation.

Packaging

5, 25 mg in poly bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
AU7358900

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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