• USA Home
  • D1377 - 2,6-Diaminopimelic acid

EMAIL THIS PAGE TO A FRIEND
D1377 Sigma-Aldrich

2,6-Diaminopimelic acid

≥98% (TLC)

Synonym: 2,6-Diaminoheptanedioic acid

  • CAS Number 583-93-7

  • Linear Formula HOOCCH(NH2)(CH2)3CH(NH2)COOH

  • Molecular Weight 190.20

  •  Beilstein/REAXYS Number 1787719

  •  EC Number 209-524-6

  •  MDL number MFCD00002637

  •  PubChem Substance ID 24893417

  •  NACRES NA.26

Purchase

Properties

Related Categories Biochemicals and Reagents, Chemical Biology, Chemical Synthesis, Dipeptides, Dipeptides and Tripeptides,
Quality Level   200
assay   ≥98% (TLC)
form   powder
application(s)   peptide synthesis: suitable
  thin layer chromatography (TLC): suitable
color   white to off-white
mp   ~295 °C (dec.) (lit.)
SMILES string   NC(CCCC(N)C(O)=O)C(O)=O
InChI   1S/C7H14N2O4/c8-4(6(10)11)2-1-3-5(9)7(12)13/h4-5H,1-3,8-9H2,(H,10,11)(H,12,13)
InChI key   GMKMEZVLHJARHF-UHFFFAOYSA-N

Description

General description

2,6-Diaminopimelic acid is produced in bacteria and is a component of cell wall. It is also synthesized by higher plants.

Application

2,6-Diaminopimelic acid (DAP) has been used:
• as a supplement in glucose minimal media for screening Bacillus subtilis(44)
• as a component of lysogeny broth (LB) agar for screening E coli transformants(45)
• as a standard in thin layer chromatography for the characterization of DAP isoforms from Streptomyces strains(46)

Biochem/physiol Actions

2,6-Diaminopimelic acid is essential for microbial metabolism and is a potential marker for quantification of microbial proteins. It is a sensitive and reliable marker and is majorly quantified using gradient high-performance liquid chromatography (HPLC).

Other Notes

Mixture of LL-, DD- and meso-isomers.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D1377.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?