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D2162 Sigma-Aldrich

Diabetes Associated Peptide Amide human

≥97% (HPLC)

Synonym: Amylin, DAP, IAPP, Insulinoma or Islet amyloid polypeptide

  • CAS Number 122384-88-7

  • Empirical Formula (Hill Notation) C165H261N51O55S2

  • Molecular Weight 3903.28

  •  MDL number MFCD00081345

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Properties

Related Categories Amylins, Cell Biology, Cell Signaling and Neuroscience, Gastrointestinal Peptides, Obesity Peptides,
assay   ≥97% (HPLC)
storage temp.   −20°C
Gene Information   human ... IAPP(3375)

Description

Amino Acid Sequence

Lys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Ala-Ile-Leu-Ser-Ser-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2 [Disulfide bridge: 2-7]

Biochem/physiol Actions

Islet amyloid polypeptide (IAPP) is a hormone coexpressed with insulin by pancreatic β-cells. IAPP is used to study the mechanisms of amyloid deposition and its role in molecular misfolding processes expecially in conditions such as diabetes type II.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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