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D2510 Sigma-Aldrich

Deoxycholic acid

≥98% (HPLC)

Synonym: 3α,12α-Dihydroxy-5β-cholanic acid, 7-Deoxycholic acid, Desoxycholic acid

  • CAS Number 83-44-3

  • Empirical Formula (Hill Notation) C24H40O4

  • Molecular Weight 392.57

  •  Beilstein/REAXYS Number 3219882

  •  EC Number 201-478-5

  •  MDL number MFCD00003673

  •  PubChem Substance ID 24893692

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Properties

Related Categories Anionic Detergents, Antigen-Vaccine Preparation, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents,
description   anionic
InChI Key   KXGVEGMKQFWNSR-LLQZFEROSA-N
assay   ≥98% (HPLC)
mol wt   392.57 g/mol
mp   171-174 °C (lit.)
Gene Information   human ... ATIC(471)

Description

General description

Deoxycholic acid is a proinflammatory agent.

Application

Deoxycholic acid has been used in a study to assess a pH-Responsive Mechanism of a Deoxycholic Acid and Folate Co-Modified Chitosan Micelle under Cancerous Environment. It has also been used in a study to investigate dose-dependent anti-inflammatory effect of ursodeoxycholic acid in experimental colitis.

Packaging

10, 100, 500 g in poly bottle

Biochem/physiol Actions

Bile Acid

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. D2510.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
FZ2100000

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Articles

BACSMLS Online Plate Map

BACSMLS compounds are conveniently provided at 5µg per well, enough for multiple injections. These are high purity (>95%) compounds supplied in an economical, ready to use format. Compounds are arran...
Keywords: Metabolites

Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

Bile acids are increasingly recognized as playing an important signaling role in the control of immune response and energy metabolism. Recently, there has been interest in measuring bile acid concent...
Clare Glicksman, Michael Wright, Dave Bell, and Anders Fridström
Reporter US, Volume 33.1
Keywords: Bacterial conjugations, Clinical, High performance liquid chromatography, Hormones, Mass spectrometry, Metabolism, Separation, Thin layer chromatography

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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