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D2819 Sigma-Aldrich

Difloxacin hydrochloride

Synonym: 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-7-(4-methylpiperazino)-4-oxo-3-quinolinecarboxylic acid hydrochloride

  • CAS Number 91296-86-5

  • Empirical Formula (Hill Notation) C21H19F2N3O3 · HCl

  • Molecular Weight 435.85

  •  MDL number MFCD03840489

  •  PubChem Substance ID 329798755

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Biochemicals and Reagents,
InChI Key   JFMGBGLSDVIOHL-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
solubility   H2O: 5 mg/mL
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   room temp

Description

Biochem/physiol Actions

Difloxacin inhibits bacterial DNA gyrase and the topoisomerase II enzyme, which inhibits DNA replication and transcription

Fluoroquinolone antibacterial compound.

Packaging

1 g in poly bottle

Application

Difloxacin is a fluoroquinolone antibiotic commonly used in veterinary medicine. It is a potential treatment for Chlamydia trachomatis infections and chronic Q fever in humans. It has been used to study how potential supplementation (magnesium) may reduce quinolone-induced damage in the horse and dog models.

General description

Chemical structure: fluoroquinolone

Other Notes

Keep container tightly closed in a dry and well-ventilated place.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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