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D4268 Sigma-Aldrich

NG,NG-Dimethylarginine dihydrochloride

Synonym: asym-Dimethylarginine, ADMA

  • CAS Number 220805-22-1

  • Empirical Formula (Hill Notation) C8H18N4O2 · 2HCl

  • Molecular Weight 275.18

  •  MDL number MFCD00270857

  •  PubChem Substance ID 24278027

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Description

General description

NG,NG-Dimethylarginine dihydrochloride is a methylated arginine derivative, which is produced by the liver. It is linked to liver cirrhosis, alcoholic hepatitis and acute liver failure (ALF).

Application

NG,NG- Dimethylarginine dihydrochloride has been used:
• to study its effects on cardiovascular activities in rostral ventrolateral medulla (RVLM) in rats
• as a standard for measuring L-arginine and dimethylarginines
• to study its effects on hepatic deterioration

Packaging

10, 50 mg in poly bottle

Biochem/physiol Actions

Reversible inhibitor of nitric oxide synthetase in vivo and in vitro.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Nitric Oxide & Cell Stress Research

Exposure to harsh conditions, cellular damage, and other factors can cause stress on cells. Stress attributed directly and indirectly to oxygen is referred to as oxidative stress, which is imposed on...
Keywords: Antimicrobials, Bioactive small molecules, Cancer, Diseases, Neurodegenerative Diseases, Oxidations

Peer-Reviewed Papers
15

References

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