EMAIL THIS PAGE TO A FRIEND
D4321 Sigma-Aldrich

Dihydroeponemycin

≥98% (HPLC)

  • CAS Number 126463-64-7

  • Empirical Formula (Hill Notation) C20H36N2O6

  • Molecular Weight 400.51

  •  MDL number MFCD17215971

  •  PubChem Substance ID 329798798

  •  NACRES NA.77

Purchase

Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Calpain and Proteasome Inhibitors, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D ±35.7°
color   off-white to light tan
solubility   DMSO: ≥1 mg/mL
storage temp.   2-8°C
SMILES string   CC(C)CCCCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(CO)CO1
InChI   1S/C20H36N2O6/c1-13(2)7-5-6-8-17(25)21-16(10-23)19(27)22-15(9-14(3)4)18(26)20(11-24)12-28-20/h13-16,23-24H,5-12H2,1-4H3,(H,21,25)(H,22,27)/t15-,16-,20+/m0/s1
InChI key   IUDBVFIQSSOIDB-TWOQFEAHSA-N

Description

Packaging

1, 5 mg in glass bottle

Biochem/physiol Actions

Dihydroeponemycin is an active derivative of eponemycin an antitumor antibiotic isolated from Streptomyces hygroscopicus. Dihydroeponemycin labels the catalytic threonine residues of the immunoproteasome subunits LMP2 and LMP7 and the constitutive proteasome subunit X, while epoxomicin covalently modifies the N-terminal catalytic threonine residues of the constitutive proteasome (X and Z) and immunoproteasome (LMP7 and MECL1) subunits.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?