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D4681 Sigma-Aldrich

L-threo-Dihydrosphingosine

≥95% (TLC)

Synonym: Safingol

  • CAS Number 15639-50-6

  • Empirical Formula (Hill Notation) C18H39NO2

  • Molecular Weight 301.51

  •  MDL number MFCD00792847

  •  PubChem Substance ID 329798800

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥95% (TLC)
storage temp.   −20°C
SMILES string   CCCCCCCCCCCCCCC[C@H](O)[C@@H](N)CO
InChI   1S/C18H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h17-18,20-21H,2-16,19H2,1H3/t17-,18-/m0/s1
InChI key   OTKJDMGTUTTYMP-ROUUACIJSA-N

Description

Biochem/physiol Actions

Sphingosine kinase inhibitor; protein kinase C alpha (PKCα) -specific inhibitor; Sphingosine analog; potentiates the effect of doxorubicin (DOX) in tumor-bearing animals.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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