EMAIL THIS PAGE TO A FRIEND
D5287 Sigma-Aldrich

2′-Deoxyinosine

≥98%

Synonym: 9-(2-Deoxy-β-D-ribofuranosyl)hypoxanthine

  • CAS Number 890-38-0

  • Empirical Formula (Hill Notation) C10H12N4O4

  • Molecular Weight 252.23

  •  Beilstein/REAXYS Number 33517

  •  EC Number 212-964-1

  •  MDL number MFCD00005762

  •  PubChem Substance ID 24893935

Purchase

Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
InChI Key   VGONTNSXDCQUGY-RRKCRQDMSA-N
assay   ≥98%
impurities   inosine, essentially free
storage temp.   −20°C

Description

Application

2′-Deoxyinosine has been used in the quantification of nucleoside forms of DNA lesion in a single DNA sample by liquid chromatography tandem mass spectrometry (LC-MS/MS). It has also been used as a standard for high performance liquid chromatography analysis.

Packaging

1 g in poly bottle

100 mg in poly bottle

Biochem/physiol Actions

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. 2′-Deoxyinosine in DNA can arise from deamination of adenosine. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

2′-Deoxyinosine is a nucleoside form of hypoxanthine. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinosine is formed from nitrosative deamination by N2O3.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

???PDP_SDS_LOT_NUMBER_ERROR_MSG???

Certificate of Origin

???PDP_SDS_LOT_NUMBER_ERROR_MSG???
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?