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D5767 Sigma-Aldrich

2,2′-Dithiodipyridine

powder

Synonym: 2,2′-Dipyridyl disulfide

  • CAS Number 2127-03-9

  • Empirical Formula (Hill Notation) C10H8N2S2

  • Molecular Weight 220.31

  •  Beilstein/REAXYS Number 154629

  •  EC Number 218-343-1

  •  MDL number MFCD00006287

  •  PubChem Substance ID 24893969

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Properties

Related Categories Amino Acid Analysis, Amino Acid Analysis Reagents, Biochemicals and Reagents, Peptide Analysis and Characterization, Peptides More...
InChI Key   HAXFWIACAGNFHA-UHFFFAOYSA-N
form   powder
mp   56-58 °C (lit.)
storage temp.   2-8°C

Description

Application

2,2′-Dithiodipyridine has been used in the reconstitution of the reduced interchain disulfide bonds of monolconal antibodies. It may be used as a medium component for T cell hybridoma cell culture and as thiol crosslinking agent.

Biochem/physiol Actions

2,2′-Dithiodipyridine mediates inter-unit disulfide cross-linking. It interacts with carbon nucleophiles to yield thiopyridyl derivatives.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
UN 3335
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
Peer-Reviewed Papers
15

References

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