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D7946 Sigma-Aldrich

DIM-C-pPhOCH3

≥98% (HPLC)

Synonym: 1,1-bis(3′-Indolyl)-1-(p-methoxyphenyl)methane; 3,3′-[(4-Methoxyphenyl)methylene]bis-1H-indole

  • CAS Number 33985-68-1

  • Empirical Formula (Hill Notation) C24H20N2O

  • Molecular Weight 352.43

  •  MDL number MFCD01217840

  •  PubChem Substance ID 329798790

  •  NACRES NA.77

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, DIG-DY,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   off-white to light yellow
solubility   DMSO: ≥30 mg/mL
storage temp.   2-8°C
SMILES string   COc1ccc(cc1)C(c2c[nH]c3ccccc23)c4c[nH]c5ccccc45
InChI   1S/C24H20N2O/c1-27-17-12-10-16(11-13-17)24(20-14-25-22-8-4-2-6-18(20)22)21-15-26-23-9-5-3-7-19(21)23/h2-15,24-26H,1H3
InChI key   ZCCMKJAXOIFTHH-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

DIM-C-pPhOCH3 is a Nerve Growth Factor-Induced Bα (NGFI-Bα, Nur77) agonist

Features and Benefits

This compound is featured on the Nuclear Receptors (Non-Steroids) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Nuclear Receptors (Non-Steroids)

The receptors for several classes of non-steroidal compounds, including retinoids, thyroid hormones and vitamin D, also act as ligand-dependent transcription factors. In addition, a large number of r...
Keywords: Absorption, Apoptosis, Atomic absorption spectroscopy, Cancer, Cardiovascular, Cell proliferation, Clinical, Detoxification, Diabetes, Diseases, Gene expression, Hormones, Ligands, Lipid Metabolism, Metabolism, Metabolites, Obesity, Transcription, Transduction, Vitamins

Peer-Reviewed Papers
15

References

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