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D9250 Sigma-Aldrich

2′-Deoxyguanosine 5′-diphosphate sodium salt

≥90% (HPLC)

Synonym: dGDP

  • CAS Number 102783-74-4

  • Empirical Formula (Hill Notation) C10H15N5O10P2 · xNa+

  • Molecular Weight 427.20 (free acid basis)

  •  MDL number MFCD00057075

  •  PubChem Substance ID 24894274

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotide Analogs More...
Quality Level   200
assay   ≥90% (HPLC)
form   powder
solubility   water: 50 mg/mL, clear, colorless
storage temp.   −20°C
SMILES string   [Na].NC1=NC(=O)c2ncn(C3CC(O)C(COP(O)(=O)OP(O)(O)=O)O3)c2N1
InChI   1S/C10H15N5O10P2.Na.H/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(24-6)2-23-27(21,22)25-26(18,19)20;;/h3-6,16H,1-2H2,(H,21,22)(H2,18,19,20)(H3,11,13,14,17);;
InChI key   VLWIICGGBFZYEZ-UHFFFAOYSA-N

Description

General description

2′-Deoxyguanosine 5′-diphosphate (dGDP) is a nucleotide with guanine base, deoxyribose and two phosphate.

Application

2′-Deoxyguanosine 5′-diphosphate (dGDP) is used as a substrate of dGDP (nucleoside diphosphate) kinase (2.7.4.6) or pyruvate kinase to produce dGTP in support of DNA biosynthesis. dGDP is used as a substrate to study the kinetics of glycoprotein (gp) 1.7 expressed by bacteriophage T7.

2′-Deoxyguanosine 5′-diphosphate sodium salt has been used as a xanthosine 5′-monophosphate analog and xanthine phosphoribosyl transferase inhibitor in kinetic studies.

Packaging

25, 100 mg in poly bottle

Biochem/physiol Actions

2′-Deoxyguanosine 5′-diphosphate (dGDP) inhibits xanthine phosphoribosyl transferase (XPRT) and hypoxanthine-guanine phosphoribosyl transferase (HGPRT).

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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