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D9500 Sigma-Aldrich

2′-Deoxyguanosine 5′-monophosphate sodium salt hydrate

≥99% (HPLC)

Synonym: 5′-Deoxyguanylic acid, dGMP

  • Empirical Formula (Hill Notation) C10H14N5O7P · xNa+ · yH2O

  • Molecular Weight 347.22 (anhydrous free acid basis)

  •  MDL number MFCD00150780

  •  PubChem Substance ID 24894297

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotide Analogs More...
Quality Level   200
biological source   Porcine pancreas
  fish
assay   ≥99% (HPLC)
form   powder
solubility   water: 50 mg/mL, clear, colorless
storage temp.   −20°C
SMILES string   O.[Na+].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP(O)([O-])=O)O3)C(=O)N1
InChI   1S/C10H14N5O7P.Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;1H2/q;+1;/p-1/t4-,5+,6+;;/m0../s1
InChI key   UVKXYXSKMTUDML-FVALZTRZSA-M

Description

Application

2′-Deoxyguanosine 5′-monophosphate (dGMP) is used as a substrate of guanylate kinase(s) (EC 2.7.4.8) to form dGDP which upon phosphorylation to dGTP supports DNA biosynthesis. dGMP is use to study physiochemical characteristics of guanine based molecules.

2′-Deoxyguanosine 5′-monophosphate sodium salt hydrate has been used:
• in reversed-phase high pressure liquid chromatography (HPLC) analysis
• to determine the effects of deoxy-mononucleotides on spontaneous proliferating CaCo-2 cell lines
• to determine its capacity to stimulate immune cell growth and function and used influenza virus antigen as an immunostimulant in vitro

Packaging

1 g in poly bottle

100, 500 mg in poly bottle

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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