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  • E0406 - Anti-Estrogen-Related Receptor α antibody produced in rabbit

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E0406 Sigma-Aldrich

Anti-Estrogen-Related Receptor α antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-ERRα, Anti-NR3B1

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Epigenetics and Nuclear Signaling, Antibodies to Hormones,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 18-24 μg/mL using human kidney
species reactivity   human
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −70°C
antibody form   affinity isolated antibody
Quality Level   200
antibody product type   primary antibodies
UniProt accession no.   P11474
Gene Information   human ... ESRRA(2101)
mouse ... Esrra(26379)

Description

Immunogen

synthetic peptide corresponding to the internal domain of human estrogen-related receptor α, conjugated to KLH. The immunizing peptide has 100% homology with the mouse gene.

Physical form

Solution in phosphate buffered saline containing 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Estrogen-Related Receptors (ERR) are hormone receptors that bind estrogen response elements that in turn bind specific DNA sequences and regulate transcription. Three ERRs are known, alpha, beta and gamma, with highly conserved ligand and DNA binding sequences. ERRα is selectively expressed in kidney, heart, cerebellum, intestine and skeletal muscle. It is an important modulator of energy balance, food intake, neuropeptide levels and response to stress.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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