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E0514 Sigma-Aldrich

E-64c

Calpain Inhibitor

Synonym: (2S,3S)-trans-Epoxysuccinyl-L-leucylamido-3-methylbutane

  • CAS Number 76684-89-4

  • Empirical Formula (Hill Notation) C15H26N2O5

  • Molecular Weight 314.38

  •  MDL number MFCD00132882

  •  PubChem Substance ID 24894369

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Description

Linkage

Synthetic analog of E-64

Biochem/physiol Actions

Cysteine protease inhibitor; membrane-impermeable calpain inhibitor. Significantly reduces calpain-mediated depletion of microtubule-associated protein (MAP2) in an animal model of an ischemic brain.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
RR0404200

Documents

Certificate of Analysis

Certificate of Origin


Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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