E1024 Sigma


meets USP testing specifications

Synonym: β-Estradiol, 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin



Related Categories Analytical/Chromatography, Application Index, Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z,
mp   176-180 °C(lit.)
suitability   meets USP testing specifications
Gene Information   human ... ESR1(2099), ESR2(2100), ESRRB(2103), GPER(2852), SERPINA6(866)
mouse ... Esr1(13982), Esr2(13983), Esrra(26379)
rat ... Afp(24177), Ar(24208), Esr1(24890), Esr2(25149), Shbg(24775)



1, 25, 100 g in glass bottle

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.

Price and Availability

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Safety & Documentation

Safety Information

GHS08  GHS08
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option:
What is Product E1024, Estradiol, soluble in?    
From the product information sheet for product E8875 (, it is soluble in ethanol, acetone, dioxane, and sparingly in vegetable oils.
What is the solution stability of Product E1024, Estradiol?
From the product information sheet for product E8875 (, since this material is air sensitive, it is best to prepare solutions fresh.
What is the working range of Product E1024, Estradiol?
For cell culture applications, the working range of this compound is 0.2 - 10 ng/mL.  For cell culture tested beta-estradiol, please refer to Sigma-Aldrich Prod. Nos. E2758 and E2257.
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
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