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E1132 Sigma-Aldrich

β-Estradiol

analytical standard

Synonym: 1,3,5-Estratriene-3,17β-diol, 17β-Estradiol, 3,17β-Dihydroxy-1,3,5(10)-estratriene, Dihydrofolliculin

  • CAS Number 50-28-2

  • Empirical Formula (Hill Notation) C18H24O2

  • Molecular Weight 272.38

  •  Beilstein/REAXYS Number 1914275

  •  EC Number 200-023-8

  •  MDL number MFCD00003693

  •  PubChem Substance ID 24894389

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Properties

Related Categories Additional Standards, Analytical Standards, Analytical/Chromatography, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
grade   analytical standard
InChI Key   VOXZDWNPVJITMN-ZBRFXRBCSA-N
packaging   vial of 250 mg
mp   176-180 °C (lit.)
Gene Information   human ... ESR1(2099), ESR2(2100), ESRRA(2101), ESRRB(2103), GPER(2852), SERPINA6(866)
mouse ... Esr1(13982), Esr2(13983), Esrra(26379)
rat ... Afp(24177), Ar(24208), Esr1(24890), Esr2(25149), Shbg(24775)

Description

Packaging

1 vial in poly bottle

Biochem/physiol Actions

The major estrogen secreted by the premenopausal ovary. Estrogens direct the development of the female phenotype in embryogenesis and during puberty by regulating gene transcription and, thus, protein synthesis. It also induces the production of gonadotropins which, in turn, induce ovulation. Exposure to estradiol increases breast cancer incidence and proliferation.

Packaging

Supplied in amber screw-cap vials

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
KG2975000

Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

HPLC Analysis of Estrogens on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Estrogens on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Steroids on Ascentis® Express Biphenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Steroids on Ascentis® Express Biphenyl
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of Steroids on Ascentis® RP-Amide (Mobile phase: 55:45)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Steroids on Ascentis® RP-Amide (Mobile phase: 55:45)
Keywords: Chromatography, Clinical, High performance liquid chromatography

TLC Analysis of Anabolic Compounds on HPTLC DIOL F254s (analyte set 1)

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Anabolic Compounds on HPTLC DIOL F254s (analyte set 1)
Keywords: Clinical, Thin layer chromatography

TLC Analysis of Hormones on HPTLC Silica Gel 60 RP-18 WF254s (analyte set 2)

From our library of Articles, Sigma-Aldrich presents TLC Analysis of Hormones on HPTLC Silica Gel 60 RP-18 WF254s (analyte set 2)
Keywords: Thin layer chromatography

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