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E5750 Sigma-Aldrich

Ergocalciferol

40,000,000 USP units/g

Synonym: Calciferol, Ercalciol, Ergosterol irradiated, Irradiated ergosterol, Vitamin D2

  • CAS Number 50-14-6

  • Empirical Formula (Hill Notation) C28H44O

  • Molecular Weight 396.65

  •  Beilstein/REAXYS Number 1916682

  •  EC Number 200-014-9

  •  MDL number MFCD00166988

  •  eCl@ss 34058017

  •  PubChem Substance ID 24894344

  •  NACRES NA.79

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Linum usitatissimum (Flax), Nutrition Research, Phytochemicals by Plant (Food/Spice/Herb),
Quality Level   200
biological source   synthetic (organic)
assay   ≥97%
form   powder
specific activity   40,000,000 USP units/g
application(s)   HPLC: suitable
color   white to off-white
mp   114-118 °C (lit.)
storage temp.   2-8°C
SMILES string   CC(C)[C@@H](C)/C=C/[C@@H](C)[C@@]1([H])CC[C@@]([C@]1(C)CCC/2)([H])C2=C\C=C(C[C@@H](O)CC3)/C3=C
InChI   1S/C28H44O/c1-19(2)20(3)9-10-22(5)26-15-16-27-23(8-7-17-28(26,27)6)12-13-24-18-25(29)14-11-21(24)4/h9-10,12-13,19-20,22,25-27,29H,4,7-8,11,14-18H2,1-3,5-6H3/b10-9+,23-12+,24-13-/t20-,22+,25-,26+,27-,28+/m0/s1
InChI key   MECHNRXZTMCUDQ-RKHKHRCZSA-N
Gene Information   human ... VDR(7421)

Description

General description

Vitamin D2 or ergocalciferol is available through dietary supplements or plant sources. It is a provitamin, which is fat-soluble.

Application

Ergocalciferol has been used as a component of the diet for rats, to study its bioavailability from ultraviolet-irradiated D2-rich yeast. It has also been used as a standard for identification and quantification of vitamins, as part of a study to determine the nutritional composition of food fishes.

Packaging

1, 5, 25 g in ampule

Biochem/physiol Actions

Ergocalciferol (vitamin D2) and 25-Hydroxycholecalciferol (vitamin D3) are the two forms of vitamin D, which are activated in vivo by hydroxylation. Vitamin D2 and D3 may be used in a wide range of studies to assess their effects on function such as immune function and calcium homeostasis.

Ergocalciferol is used for antirachitic treatment. Vitamin D has an active role in bone mineralization. Severe deficiency of this vitamin has been associated with osteomalacia and rickets.

Packaging

Sealed ampule.

Quantity

1 USP unit = 1 I.U.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 2811 6.1 / PGII
WGK Germany 
WGK 2
RTECS 
KE1050000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Vitamin D and Prevention of Human Disease

Vitamin D2 (ergocalciferol) is naturally synthesized from ergosterol by invertebrates, fungi, and plants in response to ultraviolet B irradiation, while vitamin D3 synthesis (cholecalciferol) is uniq...
Chloe McClanahan
BioFiles 2009, 4.6, 4.
Keywords: Absorption, Angiogenesis, Biofiles, Biological processes, Cancer, Clinical, Gene expression, Growth factors, Hormones, Hydroxylations, Ligands, Metabolites, Transcription, Type, Vitamins

Peer-Reviewed Papers
15

References

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