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E9156 Sigma-Aldrich

Encainide hydrochloride

≥98% (HPLC), powder

Synonym: (+/-)-4-Methoxy-N-[2-[2-(1-methyl-2-piperidinyl)ethyl]phenyl]benzamide hydrochloride, MJ-9067

  • CAS Number 66794-74-9

  • Empirical Formula (Hill Notation) C22H28N2O2 · HCl

  • Molecular Weight 388.93

  •  MDL number MFCD01667688

  •  PubChem Substance ID 329799083

  •  NACRES NA.77

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Bristol-Myers Squibb, Cell Biology,
assay   ≥98% (HPLC)
form   powder
solubility   H2O: >25 mg/mL
originator   Bristol-Myers Squibb
storage temp.   2-8°C
SMILES string   Cl.COc1ccc(cc1)C(=O)Nc2ccccc2CCC3CCCCN3C
InChI   1S/C22H28N2O2.ClH/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18;/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25);1H
InChI key   OJIIZIWOLTYOBS-UHFFFAOYSA-N

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Encainide hydrochloride is a sodium channel blocker and class Ic antiarrhythmic. Encainide is a non-chiral antiarrhythmic and benzanilide derivative.

Features and Benefits

This compound was developed by Bristol-Myers Squibb. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
CV5521500

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Discover Bioactive Small Molecules for Ion Channels Research

Ion transport across the relatively impermeable lipid bilayer of the cell membrane is accomplished via membrane proteins known as ion channels, pumps and transporters. Ion channels are gated pores an...
Keywords: Biological processes, Cell signaling, Diseases, Hormones, Ligands, Neurotransmitters

Sodium Channels

Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials. A variety of toxins and chemicals are known to either block or m...
Keywords: Analgesics, Atomic absorption spectroscopy, Central Nervous System, Gene expression, Insecticides, Neurotoxins

Peer-Reviewed Papers
15

References

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