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F1177 Sigma-Aldrich

Fluorescein hyaluronic acid

>95%, powder

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates D-F, Fluorescent Conjugates,
assay   >95%
form   powder
mol wt   ~800,000 Da
color   orange
solubility   H2O: soluble 1 mg/mL
storage temp.   2-8°C

Description

Application

Fluorescein hyaluronic acid has been used in the fluorescence imaging of hyaluronic acid (HA) and dextran surface coated filmsand patterned surfaces. It has also been used in confocal fluorescence microscopy to localize hyaluronic acid in collagen/HA composite gels .

Biochem/physiol Actions

Hyaluronan macromolecules (HAs) coupled to fluorescein amine is exploited to screen the hyaluronidase activity using fluorescence correlation spectroscopy (FCS) by measuring the quenching of fluorescein-labeled HA fragments. It binds on cell surface of malignant mesothelioma derived from human tumors.

Used to bind on cell surface of malignant mesothelioma derived from human tumors.

Other Notes

From cock’s comb or by fermentation.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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