• USA Home
  • F137 - Anti-c-Fos antibody produced in rabbit

F137 Sigma

Anti-c-Fos antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder



Related Categories Alphabetical Index, Antibodies, Antibodies for Gene Regulation, Antibodies to Common Transcription Factors, Antibodies to Transcription Factors,
species reactivity   mouse
application(s)   western blot (chemiluminescent): 10 μg/mL using mouse NIH3T3 cells
clone   polyclonal
antibody form   IgG fraction of antiserum
form   lyophilized powder
mol wt   antigen mol wt 50-60 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... FOS(2353)
mouse ... Fos(14281)
biological source   rabbit
conjugate   unconjugated



synthetic peptide derived from amino acids 4-17 from the N-terminal region of human and mouse c-Fos.

Physical form

Lyophilized from phosphate buffered saline containing 0.05% sodium azide.


The antibody does not react with c-Fos in HeLa cells.

Preparation Note

Prepared using protein A.


Anti-c-Fos antibody produced in rabbit is suitable for the following applications:
• Western blotting (chemiluminescent) at a concentration of 10μg/mL using mouse NIH3T3 cells
• Immunohistochemistry
• Tissue Immunofluorescence

Features and Benefits

Antibody Bioguarantee
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.


Reconstitute with 100 μl deionized water.

Biochem/physiol Actions

c-Fos is a proto-oncogene, which is the human homolog of the retroviral oncogene v-fos. It is one of the essential transcription factors that helps in initiation of adipocyte differentiation. FOS protein expression in human glioma is found to be strong and probably plays a critical role in the progression of gliomas. c-Fos may be involved in regulating lipid synthesis. c-Fos is associated with prognosis of ovarian cancer (OvCa) by changing the adhesion of OvCa cells to peritoneal surfaces.

Price and Availability

Antibody Explorer

Explore with Confidence
Safety & Documentation

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  nwg
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Inflammation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?