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F3388 Sigma-Aldrich

Ferric citrate

BioReagent, suitable for cell culture

Synonym: Iron(III) citrate hydrate, Iron(III) citrate

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Properties

Related Categories Cell Culture, Miscellaneous Reagents and Supplements, Reagents and Supplements More...
InChI Key   NPFOYSMITVOQOS-UHFFFAOYSA-K
product line   BioReagent
suitability   suitable for cell culture

Description

Application

Ferric citrate provides a source of iron used in cell culture applications. It provides iron in a less toxic form than free iron salts. Ferric citrate has been used as medium supplement in human osteosarcoma cell (U2OS) culture, human embryonic kidney (HEK293) cells and adult primary cardiomyocytes.

Packaging

1 kg in poly bottle

250 g in poly bottle

Biochem/physiol Actions

Ferric citrate is used as a component of protein-free medium. It is used as a substitute for transferrin in mouse hybridomas culture. Ferric citrate enhances IgM production. It indirectly stimulates the mitogen-activated protein kinase (MAPK) by favoring high amphiregulin oncoprotein levels in colon cancer.  Ferric citrate is effective in binding to phosphate in patients with dialysis-dependent chronic kidney disease.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Cell Culture Guide
Protocols & Articles

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Peer-Reviewed Papers
15

References

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