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  • F3418 - Monoclonal Anti-Cytokeratin, pan−FITC antibody produced in mouse

F3418 Sigma-Aldrich

Monoclonal Anti-Cytokeratin, pan−FITC antibody produced in mouse

clone C-11, purified immunoglobulin, buffered aqueous solution

Synonym: Monoclonal Anti-Pan Cytokeratin

  •  NACRES NA.41



Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cell and Organelle Proteins, Antibodies to Cytokeratins,
conjugate   FITC conjugate
clone   C-11, monoclonal
biological source   mouse
application(s)   direct immunofluorescence: 1:50 using PtK2 cells
  immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50 using human placenta
  western blot: suitable
species reactivity   human, mouse, rat, bovine, frog, kangaroo rat
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   purified immunoglobulin
isotype   IgG1
Quality Level   200
antibody product type   primary antibodies
storage condition   protect from light


General description

Cytokeratins are the intermediate filaments of endocrine cells. These proteins belong to the intermediate filament (10 nm) superfamily of cytoskeletal proteins. Cytokeratins are the largest and most complex group of intermediate filaments. The family consists of at least 30 proteins with molecular weights ranging from 40kDa to 68kDa.


keratin-enriched preparation from cultured human epidermoid carcinoma cell line A431.


Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Immunohistochemistry (1 paper)

Monoclonal Anti-Cytokeratin, pan−FITC antibody has been used in immunocytochemistry and has also been used to visualize lung epithelial cells.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 1% BSA and 15 mM sodium azide.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Cytokeratins helps in subtyping several kinds of epithelial differentiation or for narrowing possible sites of origin for metastatic carcinomas. Cytokeratins may play an important role in transhepatic transport and canalicular secretion.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers


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