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  • F3627 - D-Fructose 6-phosphate disodium salt hydrate

F3627 Sigma-Aldrich

D-Fructose 6-phosphate disodium salt hydrate

≥98%, amorphous powder

  • CAS Number 26177-86-6 (anhydrous)

  • Empirical Formula (Hill Notation) C6H11Na2O9P · xH2O

  • Molecular Weight 304.10 (anhydrous basis)

  •  Beilstein Registry Number 5686786

  •  MDL number MFCD16661244

  •  PubChem Substance ID 329799699



Biochem/physiol Actions

Fructose-6-phosphate is a glycolytic intermediate produced by the isomerization of glucose-6-phosphate by phosphoglucoisomerase.


1, 5 g in poly bottle

100, 500 mg in poly bottle

10 mg in glass bottle


D-Fructose 6-phosphate (F6P) is a sugar intermediate of the glycolytic pathway that may be used to help identify, differentiate and characterize enzymes such as phosphofructokinase(s), pyrophosphate-dependent fructose-6-phosphate 1-phosphotransferase(s), D-fructose-6-phosphate aldolase(s), glutamine:fructose-6-phosphate amidotransferase(s) and glucosamine-6P synthase(s).

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. F3627.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Protocols & Articles


Aerobic Glycolysis and the Warburg Effect

The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
Keywords: Aerobic, Cancer, Cell proliferation, Clinical, Glycolysis, PAGE, Phosphorylations, Transcription

Glycolysis Overview

Carbohydrates synthesized during photosynthesis act as the main storage molecules of solar energy. When ingested, complex carbohydrates are enzymatically hydrolyzed to monosaccharides, such as starch...
BioFiles 2007, 2.6, 4.
Keywords: Aldol reaction, Dehydration reaction, Glycolysis, Isomerizations, Metabolism, Metabolites, Metabolomics, Phosphorylations, Photosynthesis

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Nucleotide Synthesis in Cancer Cells

Neoplastic cells are highly dependent on the de novo synthesis of nucleotides to maintain sufficient pools to support DNA replication and the production of RNA. The metabolic pathways supporting nucl...
Keywords: Biofiles, Cancer, Catalysis, Citric Acid Cycle, DNA replication, Gene expression, Glycolysis, Metabolic Pathways, Metabolism, Metabolites, Nucleotide Synthesis, PAGE, Pentose phosphate pathway, Pyrimidine synthesis, Support

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Keywords: Cell signaling, Diagnostic, Drug discovery, Metabolomics, Molecular biology

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Peer-Reviewed Papers


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