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F7016 Sigma-Aldrich

Flumequine

≥97.0% (HPLC)

  • CAS Number 42835-25-6

  • Empirical Formula (Hill Notation) C14H12FNO3

  • Molecular Weight 261.25

  •  Beilstein/REAXYS Number 490724

  •  EC Number 255-962-6

  •  MDL number MFCD00079298

  •  PubChem Substance ID 24894926

  •  NACRES NA.85

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics by Mechanism of Action,
Quality Level   200
assay   ≥97.0% (HPLC)
form   powder
color   white to off-white
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
SMILES string   CC1CCc2cc(F)cc3C(=O)C(=CN1c23)C(O)=O
InChI   1S/C14H12FNO3/c1-7-2-3-8-4-9(15)5-10-12(8)16(7)6-11(13(10)17)14(18)19/h4-7H,2-3H2,1H3,(H,18,19)
InChI key   DPSPPJIUMHPXMA-UHFFFAOYSA-N

Description

General description

Chemical structure: fluoroquinolone

Biochem/physiol Actions

Flumequine inhibits topoisomerases, which are needed for the transcription and replication of bacterial DNA. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited .

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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