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F8649 Sigma-Aldrich

Formate Dehydrogenase from Candida boidinii

lyophilized powder, 5.0-15.0 units/mg protein

Synonym: FDH, Formate:NAD+ oxidoreductase



General description

FDH is an abundant enzyme from yeast Candida boidinii (CbFDH) that plays an important role in the energy supply of methylotrophic microorganisms and in the stress response of plants.


Formate Dehydrogenase (FDH) is used for diagnostics in large scale industrial processes. Its used in the production of an unnatural amino acid, tert-L-leucine, a component of some HIV protease and matrix metalloprotease inhibitors.


50, 250, 500 units in poly bottle

Biochem/physiol Actions

Formate dehydrogenase is involved in the stress response of plants and catalyzes the reduction of NAD+ to NADH.

Unit Definition

One unit will oxidize 1.0 μmole of formate to CO2 per min in the presence of β-NAD at pH 7.6 at 37 °C.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis


Certificate of Origin


Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What solvent can Product F8649, Formate dehydrogenase from Candida boidinii be dissolved in?
Product F8649, Formate dehydrogenase from Candida boidiniican be dissolved in 50 mM phosphate buffer,pH 7.5 to 8.0,or in double distilled water. Solubility is approximately 10 mg/ml.
How do you store Formate Dehydrogenase from Candida boidinii , productF8649, once it has been solublized?
Aliquots of theenzyme Formate Dehydrogenase from Candida boidinii , product F8649,should be stable for at least 6 months when stored at -15 to -25°C, at +33°C for 1 day, and at +2 to +8°Cfor 7 days. Aliquots should be thawed only once.
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Protocols & Articles

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