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G1639 Sigma-Aldrich

D-(+)-Galactosamine hydrochloride

suitable for cell culture, BioReagent

Synonym: 2-Amino-2-deoxy-D-galactopyranose hydrochloride, D-Chondrosamine hydrochloride

  • CAS Number 1772-03-8

  • Empirical Formula (Hill Notation) C6H13NO5 · HCl

  • Molecular Weight 215.63

  •  Beilstein/REAXYS Number 3697825

  •  EC Number 217-198-1

  •  MDL number MFCD00135830

  •  PubChem Substance ID 24895072

  •  NACRES NA.75

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Properties

Related Categories Cell Culture, Miscellaneous Reagents and Supplements, Reagents and Supplements More...
Quality Level   200
biological source   fish cartilage (shark)
product line   BioReagent
assay   ≥99%
application(s)   cell culture | mammalian: suitable
impurities   Glucosamine, essentially free
solubility   water: 50 mg/mL, clear to very slightly hazy, colorless to very faintly yellow
shipped in   ambient
storage temp.   room temp
SMILES string   Cl.N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO
InChI   1S/C6H13NO5.ClH/c7-3(1-8)5(11)6(12)4(10)2-9;/h1,3-6,9-12H,2,7H2;1H/t3-,4+,5+,6-;/m0./s1
InChI key   CBOJBBMQJBVCMW-NQZVPSPJSA-N

Description

Application

D-(+)-Galactosamine hydrochloride has been used to:
• induce livery injury
• inflammatory liver injury
• acute liver failure (ALF) in mice

Packaging

1, 5 g in poly bottle

100 mg in poly bottle

Biochem/physiol Actions

Galactosamine (D-GalN) is synthesized from galactose and is potential hepatotoxic agent. D-GalN in combination with lipopolysaccharide leads to the development of lethal liver injury and hepatic failure. It sensitizes cells to the toxic effects of the cytokine in particular the tumor necrosis factor(TNF).

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
LW5500000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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