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G2785 Sigma-Aldrich

Glycitein

≥97% (HPLC)

Synonym: 4′,7-Dihydroxy-6-methoxyisoflavone, Glycetein

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Properties

Related Categories Biochemicals and Reagents, Nucleoside Analogs, Nucleosides, Nucleotides, Oligonucleotides More...
InChI Key   DXYUAIFZCFRPTH-UHFFFAOYSA-N
assay   ≥97% (HPLC)
storage temp.   −20°C

Description

Application

Glycitein has been used as standard for the analysis of soy isoflavones and metabolites in urine. It has also been used to bind to recombinant estrogen and progesterone receptors to know the relative binding affinity (RBA) for detection of potential endocrine disruptors.

Packaging

10 mg in glass insert

Biochem/physiol Actions

Glycitein is a soybean (yellow cultivar) isoflavonoid; its natural glycosides are synergistic with genistein in inducing specific gene expression. Glycitein may be used to study anti-oxidation processes at the level of gene transcription where it increases the binding of transcription factors [nuclear factor-E2-related factor 2 (Nrf2) and c-Jun] to the antioxidant response element (ARE) on HO-1 and NQO1 promoters. Glycitein may be used in combination with other isoflavonoids such as genistein and daidzein to study apoptosis.

Glycitein possesses weak estrogenic activity than other soy isoflavones.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 1)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 1)
Keywords: Chromatography, High performance liquid chromatography, Hormones, Separation

HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 2)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Isoflavones in Soy Milk on Ascentis® Express RP Amide (Milk Brand 2)
Keywords: Chromatography, High performance liquid chromatography, Hormones, Separation

HPLC Analysis of Isoflavones on Ascentis® Phenyl

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Isoflavones on Ascentis® Phenyl
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Vitamins

Peer-Reviewed Papers
15

References

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