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G3796 Sigma-Aldrich

Granisetron hydrochloride

≥98% (HPLC), solid

Synonym: 1-Methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride

  • CAS Number 107007-99-8

  • Empirical Formula (Hill Notation) C18H24N4O · HCl

  • Molecular Weight 348.87

  •  MDL number MFCD01747034

  •  PubChem Substance ID 329799917

  •  NACRES NA.77

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Properties

Related Categories Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
Quality Level   100
assay   ≥98% (HPLC)
form   solid
color   white to off-white
mp   284.0-290.0 °C
solubility   H2O: >10 mg/mL
originator   Roche
storage temp.   room temp
SMILES string   Cl.CN1[C@H]2CCC[C@@H]1C[C@@H](C2)NC(=O)c3nn(C)c4ccccc34
InChI   1S/C18H24N4O.ClH/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17;/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23);1H/t12-,13+,14-;
InChI key   QYZRTBKYBJRGJB-WQTKJZBYSA-N

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Granisetron hydrochloride helps to block nausea/emesis and abdominal pain in irritable bowel syndrome, that is stimulated by chemotherapy.

Granisetron hydrochloride is a serotonin 5-HT3 receptor antagonist and antiemetic.

Features and Benefits

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
NK7882200
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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