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G4923 Sigma-Aldrich

(E)-Guggulsterone

≥95% (HPLC), powder

Synonym: (17E)-Pregna-4,17(20)-diene-3,16-dione

  • CAS Number 39025-24-6

  • Empirical Formula (Hill Notation) C21H28O2

  • Molecular Weight 312.45

  •  MDL number MFCD01310758

  •  PubChem Substance ID 329799934

  •  NACRES NA.77

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Description

Biochem/physiol Actions

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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G5168 (Z)-Guggulsterone, ≥89% (HPLC), powder

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