EMAIL THIS PAGE TO A FRIEND
G4923 Sigma-Aldrich

(E)-Guggulsterone

≥95% (HPLC), powder

Synonym: (17E)-Pregna-4,17(20)-diene-3,16-dione

  • CAS Number 39025-24-6

  • Empirical Formula (Hill Notation) C21H28O2

  • Molecular Weight 312.45

  •  MDL number MFCD01310758

  •  PubChem Substance ID 329799934

  •  NACRES NA.77

Purchase

Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cholesterol and Cholesterol Metabolism, Drug Efflux Pumps,
Quality Level   100
assay   ≥95% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: soluble 5 mg/mL
functional group   ketone
shipped in   ambient
storage temp.   2-8°C
SMILES string   C\C=C1\C(=O)C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI   1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4-/t15-,17+,18+,20+,21-/m1/s1
InChI key   WDXRGPWQVHZTQJ-AUKWTSKRSA-N

Description

Biochem/physiol Actions

Naturally occuring bioactive plant sterol isolated from the gum resin of guggul (Commiphora wightii). Antihyperlipidemic. Induces the expression of human CYP3A.. Guggulsterone potently reverses multi-drug resistance in a number of human cancer cell lines, extending the efficacy of chemotherapy.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

G5168 (Z)-Guggulsterone, ≥89% (HPLC), powder

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?