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G5009 Sigma

γ-Globulins from bovine blood

≥99% (agarose gel electrophoresis)

Synonym: Bovine γ-Globulin



Related Categories Application Index, Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, Globulins, Plasma & Blood Proteins,
Quality Level   PREMIUM
assay   ≥99% (agarose gel electrophoresis)
composition   NaCl, ≤4%
solubility   0.9% NaCl: soluble 25 mg/mL
storage temp.   −20°C



Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.

Bovine γ-globulins were used to study the constituents and pH changes in protein rich hyaluronan solution which affect the biological properties of artificial articular joints. It is also used to determine immunoglobulin G in bovine colostrum and milk using direct biosensor SPR-immunoassay.

General description

Plasma protein fraction rich in antibodies


1, 5, 10, 25, 100 g in poly bottle

Preparation Note

Prepared from Cohn Fraction II, III

Biochem/physiol Actions

The γ-G globulins of bovine serum are categorized by anion exchange chromatography, immunoelectrophoresis, zone electrophoresis, ultracentrifugation, and analysis of the products of papain digestion. They have properties similar to analogous components of human serum. This was determined by the methods such as: gel filtration, immunoelectrophoresis, anion exchange chromatography, ultracentrifugation, and reduction with mercaptoethanol. Fast and slow γ-G globulins were classified on the basis of differences in electrophoretic migration rates, chromatographic elution positions, and biological activities (complement fixation). Bovine γ-A was conditionally found in immunoelectrophoretic analyses of serum and chromatographic fractions.

Price and Availability

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Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
What is the molecular weight of Product G5009, γ-Globulins from bovine blood?
The molecular weight of 150,000 is based on 2 heavy chains (55,000 each) and 2 light chains (20,000 each).
What is the class of immunoglobulins in Product G5009, γ-Globulins from bovine blood?
The gamma-globulin is a mixture of IgG (80%), IgM (10%), and IgA (<10%).
How do I find price and availability?
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Protocols & Articles


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