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G5146 Sigma-Aldrich

D-(+)-Glucose

Hybri-Max, powder, BioReagent, suitable for hybridoma

Synonym: Dextrose

  • CAS Number 50-99-7

  • Empirical Formula (Hill Notation) C6H12O6

  • Molecular Weight 180.16

  •  Beilstein/REAXYS Number 1724615

  •  EC Number 200-075-1

  •  MDL number MFCD00063774

  •  PubChem Substance ID 24895199

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Properties

Related Categories Aerobic Glycolysis (the Warburg Effect), Cancer Metabolism, Cancer Research, Cell Biology, Cell Culture,
grade   Hybri-Max
InChI Key   WQZGKKKJIJFFOK-DVKNGEFBSA-N
product line   BioReagent
assay   ≥99.5%
form   powder
impurities   endotoxin, tested
mp   150-152 °C (lit.)
solubility   H2O: 2g + 15 mL, clear, colorless
suitability   suitable for hybridoma
Gene Information   human ... PYGM(5837)

Description

General description

Glycogen phosphorylase (PYG) exists as brain and muscle isoform. It is expressed in astrocytes and neurons respectively. The PYGM gene is mapped to human chromosome 11q13.1.

Application

D-(+)-Glucose has been used in cell engineering. It has also been used to perform oral glucose tolerance test.

Packaging

1 kg in poly bottle

10 kg in poly drum

Biochem/physiol Actions

Glycogen phosphorylase, muscle associated (PYGM), is an important contributor to glycogenolysis. Down regulation of PYGM gene is observed in schizophrenia. Mutation in PYGM leads to McArdle disease, a glycogen storage disorder. The PYGM gene is significantly associated with energy production.

Legal Information

Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
LZ6600000

Documents

Certificate of Analysis

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Certificate of Origin

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Pipette Controller from Brand

Cell Culture Guide
Protocols & Articles

Articles

Aerobic Glycolysis and the Warburg Effect

The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
Keywords: Aerobic, Cancer, Cell proliferation, Clinical, Glycolysis, PAGE, Phosphorylations, Transcription

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Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
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Peer-Reviewed Papers
15

References

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G8769 D-(+)-Glucose solution, 45% in H2O, sterile-filtered, BioXtra, suitable for cell culture

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