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G5502 Sigma-Aldrich

Guaiacol

oxidation indicator

Synonym: 2-Methoxyphenol, Catechol monomethyl ether, Pyrocatechol monomethyl ether

  • CAS Number 90-05-1

  • Linear Formula (CH3O)C6H4OH

  • Molecular Weight 124.14

  •  Beilstein/REAXYS Number 508112

  •  EC Number 201-964-7

  •  MDL number MFCD00002185

  •  PubChem Substance ID 24895212

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Curcuma longa (Turmeric), Enzyme Substrates, Enzymes, Inhibitors, and Substrates,
vapor density   4.27 (vs air)
vapor pressure   0.11 mmHg ( 25 °C)
InChI Key   LHGVFZTZFXWLCP-UHFFFAOYSA-N
assay   ≥98.0%
form   liquid
  solid
refractive index   n20/D 1.543 (lit.)
bp   205 °C (lit.)
mp   26-29 °C (lit.)
density   1.129 g/mL at 25 °C (lit.)

Description

General description

Guaiacol, a phenolic compound, acts as a scavenger of superoxide radicals. It is produced from guaiacum or wood creosote. Guaiacol acts as a precursor to different favoring agents like, vanillin and roasted coffee. It is used as an antiseptic, analgesic and sedative drug for the treatment of dental pulp and periodontal tissue. Guaiacol enhances cell proliferation in vivo.

Application

Guaiacol has been used:
• as a substrate for peroxidase enzyme to determine its activity
• as a substrate to determine laccase activity
• as a reagent in peroxidase (POD) activity test

Packaging

1 kg in glass bottle

100, 250, 500 g in glass bottle

Biochem/physiol Actions

Guaiacol has an ability to inhibit prostaglandin biosynthesis, without causing damage to the gastrointestinal system, unlike classic NSAID (nonsteroidal anti-inflammatory drugs).

Guaiacol, along with 2,4,6-trichloroanisole, is responsible for cork taint in wine. A method has been developed for extraction and quantitation of the two compounds.

Caution

May be liquid at room temperature.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
SL7525000
Flash Point(F) 
179.6 °F
Flash Point(C) 
82 °C

Documents

Certificate of Analysis

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Certificate of Origin

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Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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