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G5668 Sigma-Aldrich

GW1929 hydrate

>98% (HPLC), solid

Synonym: N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrate

  • Empirical Formula (Hill Notation) C30H29N3O4 · xH2O

  • Molecular Weight 495.57 (anhydrous basis)

  •  PubChem Substance ID 24278789

  •  NACRES NA.77

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   >98% (HPLC)
form   solid
solubility   DMSO: 20 mg/mL
originator   GlaxoSmithKline
SMILES string   [H]O[H].CN(CCOc1ccc(C[C@H](Nc2ccccc2C(=O)c3ccccc3)C(O)=O)cc1)c4ccccn4
InChI   1S/C30H29N3O4.H2O/c1-33(28-13-7-8-18-31-28)19-20-37-24-16-14-22(15-17-24)21-27(30(35)36)32-26-12-6-5-11-25(26)29(34)23-9-3-2-4-10-23;/h2-18,27,32H,19-21H2,1H3,(H,35,36);1H2/t27-;/m0./s1
InChI key   XSITZVFUXCLFMK-YCBFMBTMSA-N
Gene Information   human ... PPARG(5468)

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

GW1929 is a high affinity agonist of PPAR-γ.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes only, pursuant to an agreement with Glaxo­Smith­Kline

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
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