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G5918 Sigma-Aldrich

GR 113808

≥98% (HPLC), solid

Synonym: 1-[2-[(Methylsulfonyl)-amino]ethyl]-4-piperidinyl]methyl 1-methyl-1H-indole-3-carboxylate

  • CAS Number 144625-51-4

  • Empirical Formula (Hill Notation) C19H27N3O4S

  • Molecular Weight 393.50

  •  MDL number MFCD00912901

  •  PubChem Substance ID 24278311

  •  NACRES NA.77

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Properties

Related Categories Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
assay   ≥98% (HPLC)
form   solid
color   white to light pink
solubility   DMSO: >20 mg/mL
originator   GlaxoSmithKline
storage temp.   2-8°C
SMILES string   Cn1cc(C(=O)OCC2CCN(CCNS(C)(=O)=O)CC2)c3ccccc13
InChI   1S/C19H27N3O4S/c1-21-13-17(16-5-3-4-6-18(16)21)19(23)26-14-15-7-10-22(11-8-15)12-9-20-27(2,24)25/h3-6,13,15,20H,7-12,14H2,1-2H3
InChI key   MOZPSIXKYJUTKI-UHFFFAOYSA-N
Gene Information   human ... HTR4(3360)
rat ... Htr3a(79246), Htr4(25324)

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

GR 113808 is a 5-HT4 serotonin receptor antagonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

Sold for research purposes under agreement from Glaxo­Smith­Kline

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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