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G6392 Sigma-Aldrich

L-Glutamine

γ-irradiated, BioXtra, suitable for cell culture

Synonym: (S)-2,5-Diamino-5-oxopentanoic acid, L-Glutamic acid 5-amide, Levoglutamide

  • CAS Number 56-85-9

  • Linear Formula H2NCOCH2CH2CH(NH2)CO2H

  • Molecular Weight 146.14

  •  Beilstein Registry Number 1723797

  •  EC Number 200-292-1

  •  MDL number MFCD00008044

  •  eCl@ss 32160406

  •  PubChem Substance ID 24895254

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Properties

Related Categories Amino Acids, Amino Acids and Vitamins, Amino acids, Apoptosis and Cell Cycle, Cell Biology,
InChI Key   ZDXPYRJPNDTMRX-VKHMYHEASA-N
sterility   γ-irradiated
product line   BioXtra
packaging   vial of 0.292 g
impurities   endotoxin, tested
mp   185 °C (dec.) (lit.)
solubility   H2O: 10 mL/vial, clear to slightly hazy
suitability   suitable for cell culture
Gene Information   rat ... Ggt1(116568)

Description

Biochem/physiol Actions

L-Glutamine is an essential amino acid that is a crucial component of culture media that serves as a major energy source for cells in culture. L-Glutamine is very stable as a dry powder and as a frozen solution. In liquid media or stock solutions, however, L-glutamine degrades relatively rapidly. Optimal cell performance usually requires supplementation of the media with L-glutamine prior to use.

L-glutamine is an essential amino acid that is a crucial component of culture media, and serves as a major energy source for cells in culture. Optimal cell performance usually requires supplementation of the medium with L-glutamine prior to use.

Packaging

50 mL amber serum vial with rubber stopper.

Reconstitution

Prepares a 200 mM solution when reconstituted to 10 mL with sterile water.

Suitability

Qualified for use in cell culture applications, especially serum-free cell culture.

Other Notes

The dipeptide L-Ala-LGln is frequently used in modern serum-free media formulations because it provides a more stable form of glutamine in vitro.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
MA2275100

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
Is the molecular weight of L-Glutamine 146.14 or 146.15? The label information changed.
Based on a molecular formula of C5H10N2O3, the molecular weight to seven significant figures is 146.1456. Over the years, this value may have been reported in Sigma-Aldrich documentation or on labels as either 146.15 (by rounding up) or 146.14 (by truncation). The material itself has not changed.
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Protocols & Articles

Articles

HPLC Analysis of Glutamine Enantiomers on Astec® CHIROBIOTIC® T (23 °C)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Glutamine Enantiomers on Astec® CHIROBIOTIC® T (23 °C)
Keywords: Chromatography, High performance liquid chromatography

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Peer-Reviewed Papers
15

References

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