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G7127 Sigma-Aldrich

Guanosine 5′-diphosphate sodium salt

Type I, ≥96% (HPLC)

Synonym: GDP

  • CAS Number 43139-22-6

  • Empirical Formula (Hill Notation) C10H15N5O11P2

  • Molecular Weight 443.20

  •  MDL number MFCD00070121

  •  PubChem Substance ID 24895291

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Description

Application

Guanosine 5′-diphosphate sodium salt has been used:
• in GTP-γ-35S functional assays
• in Y1 agonist-stimulated [35S]- guanosine-5′-O-(3-thio)triphosphate (GTPγS) functional binding
• in the expression and purification of recombinant proteins

Packaging

1 g in poly bottle

25, 100, 500 mg in poly bottle

10 mg in glass bottle

Biochem/physiol Actions

Guanosine 5′-diphosphate (GDP) is the diphosphate nucleoside of the purine guanine. GDP and GTP are involved in and may be used to study cell signaling via G-coupled protein receptors (GCPR) and guanine nucleotide exchange factors (GEF) and a variety of GTPases.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of GMP, GDP and GTP on SeQuant ZIC-HILIC
Keywords: Chromatography, High performance liquid chromatography

LC/MS Analysis of Nucleotides SeQuant ZIC-cHILIC – Effect of pH

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Nucleotides SeQuant ZIC-cHILIC – Effect of pH
Keywords: High performance liquid chromatography, Mass spectrometry

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC – Effect of Mobile Phase Buffer Concentration

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC – Effect of Mobile Phase Buffer Concentration
Keywords: High performance liquid chromatography, Mass spectrometry

LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Nucleotides on SeQuant ZIC-cHILIC
Keywords: Buffers, Building blocks, Chromatography, High performance liquid chromatography, Ion-exchange chromatography, Mass spectrometry, Reversed-phase chromatography, Separation

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

The Krebs cycle — harnessing chemical energy for cellular respiration

The tricarboxylic acid (TCA) cycle, also known as the Krebs or citric acid cycle, is the main source of energy for cells and an important part of aerobic respiration. The cycle harnesses the availabl...
Keywords: Addition reactions, Aerobic, Biochemistry, Catalysis, Citric Acid Cycle, Decarboxylations, Dehydration reaction, Diseases, Enzyme activity, Glycolysis, Hydration reaction, Lipid Metabolism, Mass spectrometry, Metabolism, Metabolites, Metabolomics, Oxidations, Phosphorylations, Respiration

Peer-Reviewed Papers
15

References

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