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G7132 Sigma-Aldrich

Sodium glycocholate hydrate

≥95% (TLC)

Synonym: 3α,7α,12α-Trihydroxy-5β-cholan-24-oic acid N-(carboxymethyl)amide sodium salt, Glycocholic acid sodium salt hydrate, N-(3α,7α,12α-Trihydroxy-24-oxocholan-24-yl)glycine sodium salt, N-Cholylglycine sodium salt

  • CAS Number 338950-81-5

  • Linear Formula C26H42NO6Na · xH2O

  • Molecular Weight 487.60 (anhydrous basis)

  •  Beilstein/REAXYS Number 3854517

  •  EC Number 212-730-9

  •  MDL number MFCD09037360

  •  PubChem Substance ID 24895292



Related Categories Anionic Detergents, Antigen-Vaccine Preparation, Bile Salts, Biochemicals and Reagents, Cell Culture,
description   anionic
assay   ≥95% (TLC)
mol wt   micellar avg mol wt 900(lit.)
aggregation number   1.9
CMC   13 mM (20-25°C)(lit.)
mp   210-215 °C (subl.) (lit.)


General description

Sodium glycocholate hydrate is a conjugated bile salt and an ionic biologic detergent.


Sodium glycocholate hydrate has been used in a study to assess serum total bile acids via a fluorimetric and enzymatic method. It has also been used in a study to investigate its effect on micelle formation and solubilization of testosterone.


1, 5, 25, 50 g in poly bottle

100, 500 mg in poly bottle

Biochem/physiol Actions

Bile Salt

Preparation Note

This product is synthetically prepared from naturally occuring cholic acid (Product No. C1129).

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles


Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

Bile Salts and Bile Salt Hydrolase

Several Lactobacillus and Bifidobacterium probiotic strains exhibit bile salt hydrolase (BSH) activity and are suspected to play a role in combating the negative effects of bile via detoxification of...
Chloe McClanahan
Biofiles Edition 6.2
Keywords: Detoxification, Probiotics, Thin layer chromatography, Titrations

Probiotics and Human Health

At the beginning of the 20th century, probiotics were thought to have a beneficial effect to the host by improving the intestinal microbial balance. Through his studies and observations, the Russian ...
Chloe McClanahan
BioFiles Edition 6.2
Keywords: AGE, Absorption, Adhesion, Amplification, Anaerobic, Antimicrobials, Cancer, Carcinogens, Cell proliferation, Chromatography, Coagulation, Detoxification, Diagnostic, Diseases, Enzyme activity, Fermentation, Gas chromatography, Gastrointestinal, High performance liquid chromatography, Inflammation, Magnetic resonance spectroscopy, Metabolism, Metabolites, Molecular biology, Nucleic acid hybridization, PAGE, Pharmaceutical, Phosphorylations, Polymerase chain reaction, Prebiotics, Probiotics, Reductions, Respiratory, Sequencing, Thin layer chromatography, Titrations


Enzymatic Assay of Choloylglycine Hydrolase

To standardize a procedure for the determination of the enzymatic assay of choloylglycine hydrolase.
Keywords: Enzyme activity

Peer-Reviewed Papers


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