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G7516 Sigma

γ-Globulins from bovine blood

≥97% (agarose gel electrophoresis)

Synonym: Bovine γ-Globulin



Related Categories Application Index, Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, Globulins, Plasma & Blood Proteins,
Quality Level   PREMIUM
assay   ≥97% (agarose gel electrophoresis)
composition   NaCl, ≤5%
solubility   0.9% NaCl: soluble 50 mg/mL
storage temp.   −20°C



Bovine γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.

γ-globulin has been used as an immunological challenge in studies of mechanisms of immunotolerance.
Bovine γ-globulins were used to study the constituents and pH changes in protein rich hyaluronan solution affecting the bio-tribological properties of artificial articular joints. It is also used to determine immunoglobulin G in bovine colostrum and milk by direct biosensor SPR-immunoassay.
Bovine γ-globulin was used in rapid screening for monensin residues in poultry plasma by a dry reagent dissociation enhanced lanthanide fluoroimmunoassay. It was also tested for the effects of solution properties on solute and permeate flux in bovine serum albumin-IgG ultrafiltration.

General description

Plasma protein fraction rich in antibodies

The γG globulins of bovine serum are categorized by anion exchange chromatography, immunoelectrophoresis, zone electrophoresis, ultracentrifugation, and analysis of the products of papain digestion. They have properties similar to analogous components of human serum. This was determined by the methods such as: gel filtration, immunoelectrophoresis, anion exchange chromatography, ultracentrifugation, and reduction with mercaptoethanol. Fast and slow γG globulins were classified on the basis of differences in electrophoretic migration rates, chromatographic elution positions, and biological activities (complement fixation). Bovine γA was conditionally found in immunoelectrophoretic analyses of serum and chromatographic fractions.


1, 5, 10, 25, 100 g in poly bottle

Preparation Note

Prepared from plasma

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Safety Information

NONH for all modes of transport
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Certificate of Analysis

Certificate of Origin

Protocols & Articles


Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

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